SKU: CAG 5

Cagrilintide 10mg

Product Overview Cagrilintide 10mg is a high-purity, lyophilized (freeze-dried) synthetic peptide analog of human amylin, engineered as a long-acting dual agonist for amylin and calcitonin receptors. With a molecular formula of C₁₉₄H₃₁₂N₅₄O₅₉S₂ and an approximate molecular weight of 4,409 Da, this compound features a 20-residue amylin-derived backbone modified with a C20 di-acid fatty acid side chain for enhanced albumin binding and extended half-life (159–195 hours in research models). Supplied in a sealed, sterile vial, it is ideal for in vitro laboratory studies exploring metabolic pathways, receptor signaling, and neuroendocrine mechanisms.

Key Research Applications

• Appetite Regulation and Satiety Studies: Investigates interactions with brain receptors (e.g., nucleus tractus solitarius and area postrema) to model hunger suppression and energy intake reduction in experimental settings.
• Metabolic and Weight Management Research: Examines effects on gastric emptying, caloric intake, and fat loss, with preclinical data indicating up to 17% synergistic weight reduction when combined with GLP-1 agonists like semaglutide.
• Glycemic Control and Endocrine Investigations: Explores impacts on glucose homeostasis, insulin co-secretion dynamics, and potential implications for obesity, type 2 diabetes, liver function, and cardiovascular health models.
• Neuroendocrine and Receptor Signaling Analysis: Supports in-depth assays on dual-agonist profiles for sustained activity in appetite, energy balance, and cognitive decline studies.