SKU: M O T S-C 10
$115.00
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MOTS-C 10mg
Product Overview MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded by the mitochondrial genome. Naturally expressed in response to metabolic stress or exercise, MOTS-C plays a key role in regulating cellular energy homeostasis by translocating to the nucleus and modulating genes involved in antioxidant responses and metabolic adaptation. This lyophilized 10mg vial is provided in high-purity (>99%) form, suitable for in vitro laboratory investigations into mitochondrial function and related pathways.
Key Research Applications
- Metabolic Regulation: Investigates insulin sensitivity and glucose uptake mechanisms in models of diet-induced obesity and type 2 diabetes.
- Aging and Longevity: Explores anti-aging effects, including protection against age-related mitochondrial decline and enhancement of stress resilience.
- Inflammation and Oxidative Stress: Studies modulation of pro-inflammatory cytokines (e.g., IL-6, TNF-α) and antioxidant gene expression in cellular stress models.
- Cardiovascular and Bone Health: Examines potential roles in cardiac hypertrophy prevention and osteoblast differentiation for bone formation research.
- Neuroprotection: Probes memory enhancement and attenuation of amyloid-beta or LPS-induced deficits in neurodegenerative models.
Description
Specifications
- Format: 10mg lyophilized powder in a sterile glass vial.
- Purity: ≥99%
- Molecular Formula: C101H152N28O22S2 (MRWQEMGYIFYPRKLR).
- Storage: -20°C (stable for 24 months); reconstitute with bacteriostatic water for short-term use. Store in a freezer. Once reconstituted, store in a refrigerator. Keep in dry place away from direct sunlight. Keep tightly sealed to maintain integrity.
- Solubility: Soluble in aqueous solutions (e.g., saline or PBS).
Important Disclaimer This product is strictly for research use only. It is not intended for human or animal consumption, diagnostic procedures, or therapeutic applications. Not FDA-approved for clinical use. Researchers must comply with all applicable local regulations and institutional biosafety guidelines. Consult safety data sheets (SDS) for handling precautions.
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